Screening and mechanistic study of key sites of the hemagglutinin-neuraminidase protein related to the virulence of Newcastle disease virus

Screening and mechanistic study of key sites of the hemagglutinin-neuraminidase protein related to the virulence of Newcastle disease virus

Newcastle disease is a kind of avian infectious disease caused by Newcastle disease virus (NDV). The virulence of NDV is dependent mainly on the fusion (F) protein and hemagglutinin-neuraminidase (HN) protein. The genomes of 2 viruses, NDV-Blackbird and NDV-Dove, are 99.9% similar, while NDV-Blackbi...

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Bibliographic Details
Main Authors: Chuanqi Yan, Haijin Liu, Yanqing Jia, Daguia-Wenam Prince-Theodore, Mengqing Yang, Fathalrhman Eisa Addoma Adam, Juan Ren, Xuhong Cao, Xinglong Wang, Sa Xiao, Shuxia Zhang, Zengqi Yang
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Poultry Science
Subjects:
Newcastle disease virus (NDV)
hemagglutinin-neuraminidase (HN) protein
virulence
cell fusion promotion
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579120302546

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http://www.sciencedirect.com/science/article/pii/S0032579120302546

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