FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells

The inhibitory effect of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters DAP12 and FcεRI γ-chain (FcRγ) has been found in many immune functions. Herein, we have further explored the role of these adapters in C-type lectin receptors response. We identified that FcRγ, but not...

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Bibliographic Details
Main Authors: Yi-Gen Pan, Yen-Ling Yu, Chi-Chien Lin, Lewis L. Lanier, Ching-Liang Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01424/full