Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury

Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury

Myocardial infarction (MI) accounts for a significant proportion of death and morbidity in aged individuals. The risk for MI in females increases as they enter the peri-menopausal period, generally occurring in middle-age. Cytochrome (CYP) 450 metabolizes N-3 and N-6 polyunsaturated fatty acids (PUF...

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Bibliographic Details
Main Authors: K. Lockhart Jamieson, Ahmed M. Darwesh, Deanna K. Sosnowski, Hao Zhang, Saumya Shah, Pavel Zhabyeyev, Jun Yang, Bruce D. Hammock, Matthew L. Edin, Darryl C. Zeldin, Gavin Y. Oudit, Zamaneh Kassiri, John M. Seubert
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
soluble epoxide hydrolase
ischemic injury
failing heart
explanted hearts
sex differences
aging
Online Access:https://www.mdpi.com/1422-0067/22/4/1691

Internet

https://www.mdpi.com/1422-0067/22/4/1691

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