Overexpression of glycosyltransferase 8 domain containing 2 confers ovarian cancer to CDDP resistance by activating FGFR/PI3K signalling axis

Overexpression of glycosyltransferase 8 domain containing 2 confers ovarian cancer to CDDP resistance by activating FGFR/PI3K signalling axis

Abstract It has been reported that chemotherapy resistance mainly contributed to treatment failure and poor survival in patients with ovarian cancer. Therefore, clarifying the molecular mechanism and identifying effective strategies to overcome drug resistance may play an important clinical impact o...

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Bibliographic Details
Main Authors: Shuting Huang, Suiying Liang, Guandi Chen, Jing Chen, Keli You, Haiyan Ye, Zhigang Li, Shanyang He
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-021-00343-w

Internet

https://doi.org/10.1038/s41389-021-00343-w

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