Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR.

<h4>Introduction</h4>Adipose tissue is considered an important metabolic tissue, in charge of energy storage as well as being able to act in systemic homeostasis and inflammation. Epigenetics involves a series of factors that are important for gene regulation or for chromatin structure,...

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Bibliographic Details
Main Authors: Daniel Castellano-Castillo, Pierre-Damien Denechaud, Lluis Fajas, Isabel Moreno-Indias, Wilfredo Oliva-Olivera, Francisco Tinahones, María Isabel Queipo-Ortuño, Fernando Cardona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215083