Yolk-sac-derived macrophages progressively expand in the mouse kidney with age

Yolk-sac-derived macrophages progressively expand in the mouse kidney with age

Renal macrophages represent a highly heterogeneous and specialized population of myeloid cells with mixed developmental origins from the yolk-sac and hematopoietic stem cells (HSC). They promote both injury and repair by regulating inflammation, angiogenesis, and tissue remodeling. Recent reports hi...

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Bibliographic Details
Main Authors: Shintaro Ide, Yasuhito Yahara, Yoshihiko Kobayashi, Sarah A Strausser, Kana Ide, Anisha Watwe, Shengjie Xu-Vanpala, Jamie R Privratsky, Steven D Crowley, Mari L Shinohara, Benjamin A Alman, Tomokazu Souma
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
macrophage ontogeny
aging
kidney
Online Access:https://elifesciences.org/articles/51756

Internet

https://elifesciences.org/articles/51756

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