A novel preprocessing method using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF mass spectrometry data.

A novel preprocessing method using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF mass spectrometry data.

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MOTIVATION: Mass spectrometry is a high throughput, fast, and accurate method of protein analysis. Using the peaks detected in spectra, we can compare a normal group with a disease group. However, the spectrum is complicated by scale shifting and is also full of noise. Such shifting makes the spectr...

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Bibliographic Details
Main Authors: Li-Ching Wu, Hsin-Hao Chen, Jorng-Tzong Horng, Chen Lin, Norden E Huang, Yu-Che Cheng, Kuang-Fu Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2930864?pdf=render

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http://europepmc.org/articles/PMC2930864?pdf=render

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