X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB
Guan and Hariharan report two crystal structures of melibiose transporter MelB in complex with substrate analogs, nitrophenyl-galactoside, and dodecyl-melibioside. Both structures revealed similar specific site for sugar recognition and resolved the cation-binding pocket, advancing the understanding...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02462-x |