Right Atrial Myocardial Remodeling in Children With Atrial Septal Defect Involves Inflammation, Growth, Fibrosis, and Apoptosis

Right Atrial Myocardial Remodeling in Children With Atrial Septal Defect Involves Inflammation, Growth, Fibrosis, and Apoptosis

Introduction: Myocardial remodeling due to large atrial septum defect (ASD) is macroscopically characterized by dilation of the right-sided cardiac cavities secondary to volume overload, the cellular mechanisms of which are not yet understood. We postulated that inflammation, fibrosis, and cell deat...

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Bibliographic Details
Main Authors: Hatem Rouatbi, Nesrine Farhat, Ruth Heying, Arlette Gérard, Jaime F. Vazquez-Jimenez, Marie-Christine Seghaye
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pediatrics
Subjects:
myocardial remodeling
congenital heart disease
atrial septum defect
inflammation
growth
fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00040/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2020.00040/full

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