Thymic plasmacytoid dendritic cells are susceptible to productive HIV-1 infection and efficiently transfer R5 HIV-1 to thymocytes <it>in vitro</it>

<p>Abstract</p> <p>Background</p> <p>HIV-1 infection of the thymus contributes to the defective regeneration and loss of CD4<sup>+ </sup>T cells in HIV-1-infected individuals. As thymic dendritic cells (DC) are permissive to infection by HIV-1, we examined t...

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Bibliographic Details
Main Authors: Wright Edwina, Solomon Ajantha, Akkina Ramesh, Lal Luxshimi, Evans Vanessa A, Lewin Sharon R, Cameron Paul U
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/8/1/43