Deep Learning Reveals Key Immunosuppression Genes and Distinct Immunotypes in Periodontitis

Deep Learning Reveals Key Immunosuppression Genes and Distinct Immunotypes in Periodontitis

BackgroundPeriodontitis is a chronic immuno-inflammatory disease characterized by inflammatory destruction of tooth-supporting tissues. Its pathogenesis involves a dysregulated local host immune response that is ineffective in combating microbial challenges. An integrated investigation of genes invo...

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Bibliographic Details
Main Authors: Wanchen Ning, Aneesha Acharya, Zhengyang Sun, Anthony Chukwunonso Ogbuehi, Cong Li, Shiting Hua, Qianhua Ou, Muhui Zeng, Xiangqiong Liu, Yupei Deng, Rainer Haak, Dirk Ziebolz, Gerhard Schmalz, George Pelekos, Yang Wang, Xianda Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
deep learning
autoencoder (AE)
periodontitis
immunosuppression genes
therapeutic targets
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.648329/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.648329/full

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