Hyperplastic Polyps Are Innocuous Lesions in Hereditary Nonpolyposis Colorectal Cancers

Hyperplastic Polyps Are Innocuous Lesions in Hereditary Nonpolyposis Colorectal Cancers

Aims. To compare methylation profiles, protein expression, and microsatellite instability (MSI) of sporadic, HNPCC, and familial hyperplastic polyps (HPs). Methods. Methylation-specific PCR (MSP) and pyrosequencing assessed p16, MGMT, hMLH-1, MINT 1, and MINT 31 methylation. IHC (Immunohistochemistr...

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Bibliographic Details
Main Authors: D. Speake, J. O'Sullivan, D. G. Evans, F. Lalloo, J. Hill, R. F. T. McMahon
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Surgical Oncology
Online Access:http://dx.doi.org/10.1155/2011/653163

Internet

http://dx.doi.org/10.1155/2011/653163

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