Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer's disease

Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer's disease

AMP-activated protein kinase (AMPK) is a molecular sensor that is critical for the maintenance of cellular energy homeostasis, disruption of which has been indicated in multiple neurodegenerative diseases including Alzheimer's disease (AD). Mammalian AMPK is a heterotrimeric complex and its enz...

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Bibliographic Details
Main Authors: Xin Wang, Xueyan Zhou, Beth Uberseder, Jingyun Lee, Caitlin S. Latimer, Cristina M. Furdui, C. Dirk Keene, Thomas J. Montine, Thomas C. Register, Suzanne Craft, Carol A. Shively, Tao Ma
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Neurobiology of Disease
Subjects:
AMPK
Non-human primate
Alzheimer's disease
AMPK isoform
Protein synthesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002126

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http://www.sciencedirect.com/science/article/pii/S0969996121002126

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