Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection.

Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection.

The low pathogenicity and replicative potential of HIV-2 are still poorly understood. We investigated whether HIV-2 reservoirs might follow the peculiar distribution reported in models of attenuated HIV-1/SIV infections, i.e. limited infection of central-memory CD4 T lymphocytes (TCM). Antiretrovira...

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Bibliographic Details
Main Authors: Assia Samri, Charlotte Charpentier, Mariama Sadjo Diallo, Mélanie Bertine, Sophie Even, Véronique Morin, Anne Oudin, Christophe Parizot, Gilles Collin, Anne Hosmalin, Rémi Cheynier, Rodolphe Thiébaut, Sophie Matheron, Fideline Collin, Rima Zoorob, Françoise Brun-Vézinet, Brigitte Autran, ANRS CO5 IMMUNOVIR-2 Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007758

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https://doi.org/10.1371/journal.ppat.1007758

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