STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice.

In recent years, there has been an increasing interest in immunomodulatory therapy as a means to treat various conditions, including infectious diseases. For instance, Toll-like receptor (TLR) agonists have been evaluated for treatment of genital herpes. However, although the TLR7 agonist imiquimod...

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Bibliographic Details
Main Authors: Morten K Skouboe, Alice Knudsen, Line S Reinert, Cedric Boularan, Thierry Lioux, Eric Perouzel, Martin K Thomsen, Søren R Paludan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5897032?pdf=render