Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration

Altered subchondral bone and articular cartilage interactions have been implicated in the pathogenesis of osteoarthritis (OA); however, the mechanisms remain unknown. Exosomes are membrane-derived vesicles that have recently been recognized as important mediators of intercellular communication. Here...

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Bibliographic Details
Main Authors: Xiaoxin Wu, Ross Crawford, Yin Xiao, Xinzhan Mao, Indira Prasadam
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/251