Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration
Altered subchondral bone and articular cartilage interactions have been implicated in the pathogenesis of osteoarthritis (OA); however, the mechanisms remain unknown. Exosomes are membrane-derived vesicles that have recently been recognized as important mediators of intercellular communication. Here...
Main Authors: | Xiaoxin Wu, Ross Crawford, Yin Xiao, Xinzhan Mao, Indira Prasadam |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/2/251 |
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