Improving transgene expression and CRISPR‐Cas9 efficiency with molecular engineering‐based molecules

Improving transgene expression and CRISPR‐Cas9 efficiency with molecular engineering‐based molecules

Abstract As a novel and robust gene‐editing tool, the Clustered Regularly Interspaced Short Palindromic Repeats CRISPR‐associated protein 9 (CRISPR‐Cas9) system has revolutionized gene therapy. Plasmid vector delivery is the most commonly used method for integrating the CRISPR‐Cas9 system into cells...

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Bibliographic Details
Main Authors: Hengji Zhan, Mengting Ding, Qun Zhou, Aolin Li, Zhiming Cai, Weiren Huang, Yuchen Liu
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Clinical and Translational Medicine
Subjects:
CRISPR‐Cas9
innate immune response
mammalian cells
transgene expression
Online Access:https://doi.org/10.1002/ctm2.194

Internet

https://doi.org/10.1002/ctm2.194

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