Detection of neuroinflammation before selective neuronal loss appearance after mild focal ischemia using [18F]DPA-714 imaging

Detection of neuroinflammation before selective neuronal loss appearance after mild focal ischemia using [18F]DPA-714 imaging

Abstract Background Translocator protein (TSPO) imaging can be used to detect neuroinflammation (including microglial activation) after acute cerebral infarction. However, longitudinal changes of TSPO binding after mild ischemia that induces selective neuronal loss (SNL) without acute infarction are...

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Bibliographic Details
Main Authors: Natsumi Miyajima, Miwa Ito, Takemi Rokugawa, Hitoshi Iimori, Sotaro Momosaki, Shigeki Omachi, Eku Shimosegawa, Jun Hatazawa, Kohji Abe
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:EJNMMI Research
Subjects:
Mild ischemia
Translocator protein
Selective neuronal loss
[18F]DPA-714 binding
Online Access:http://link.springer.com/article/10.1186/s13550-018-0400-x

Internet

http://link.springer.com/article/10.1186/s13550-018-0400-x

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