Alternate subunit assembly diversifies the function of a bacterial toxin

Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory animals.

Bibliographic Details
Main Authors: Casey C. Fowler, Gabrielle Stack, Xuyao Jiao, Maria Lara-Tejero, Jorge E. Galán
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11592-0