Advances in understanding the renin-angiotensin-aldosterone system (RAAS) in blood pressure control and recent pivotal trials of RAAS blockade in heart failure and diabetic nephropathy [version 1; referees: 3 approved]

The renin-angiotensin-aldosterone system (RAAS) plays a fundamental role in the physiology of blood pressure control and the pathophysiology of hypertension (HTN) with effects on vascular tone, sodium retention, oxidative stress, fibrosis, sympathetic tone, and inflammation. Fortunately, RAAS blocki...

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Bibliographic Details
Main Authors: Lama Ghazi, Paul Drawz
Format: Article
Language:English
Published: F1000 Research Ltd 2017-03-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-297/v1