A comparative study of age-related hearing loss in wild type and insulin-like growth factor I deficient mice

A comparative study of age-related hearing loss in wild type and insulin-like growth factor I deficient mice

Insulin-like growth factor-I (IGF-I) belongs to the family of insulin-related peptides that fulfils a key role during the late development of the nervous system. Human<em> IGF1</em> mutations cause profound deafness, poor growth and mental retardation. Accordingly,<em> Igf1&min...

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Bibliographic Details
Main Authors: Raquel Riquelme, Rafael Cediel, Julio Contreras, Lourdes Rodríguez-de La Rosa, Silvia Murillo-Cuesta, Catalina Hernandez, Jose M Zubeldia, Sebastian Cerdan, Isabel Varela-Nieto
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-06-01
Series:Frontiers in Neuroanatomy
Subjects:
Deafness
Ageing
auditory brainstem responses
in vivo brain imaging
presbyacusis
Igf1-/- null mouse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2010.00027/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnana.2010.00027/full

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