Ablation of C/EBP homologous protein does not protect T17M RHO mice from retinal degeneration.

Despite the proposed link between ablation of the CHOP protein and delay of the onset of ER stress-mediated disorders including diabetes, Alzheimer Disease, and cardiac hypertrophy, the role of CHOP protein in photoreceptor cell death associated with Autosomal Dominant Retinitis Pigmentosa (ADRP) ha...

Full description

Bibliographic Details
Main Authors: Sonali Nashine, Yogesh Bhootada, Alfred S Lewin, Marina Gorbatyuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3640035?pdf=render