Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells.

Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells.

Myeloproliferative neoplasms (MPN)-such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF)-are typically diseases of the elderly caused by acquired somatic mutations. However, it is largely unknown how the malignant clone interferes with normal hematopoiesis. In this s...

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Bibliographic Details
Main Authors: Richard K Lubberich, Thomas Walenda, Tamme W Goecke, Klaus Strathmann, Susanne Isfort, Tim H Brümmendorf, Steffen Koschmieder, Wolfgang Wagner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5979002?pdf=render

Internet

http://europepmc.org/articles/PMC5979002?pdf=render

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