Creation of lung-targeted dexamethasone immunoliposome and its therapeutic effect on bleomycin-induced lung injury in rats.

Creation of lung-targeted dexamethasone immunoliposome and its therapeutic effect on bleomycin-induced lung injury in rats.

OBJECTIVE: Acute lung injury (ALI), is a major cause of morbidity and mortality, which is routinely treated with the administration of systemic glucocorticoids. The current study investigated the distribution and therapeutic effect of a dexamethasone(DXM)-loaded immunoliposome (NLP) functionalized w...

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Bibliographic Details
Main Authors: Xue-Yuan Chen, Shan-Mei Wang, Nan Li, Yang Hu, Yuan Zhang, Jin-Fu Xu, Xia Li, Jie Ren, Bo Su, Wei-Zhong Yuan, Xin-Rong Teng, Rong-Xuan Zhang, Dian-Hua Jiang, Xavier Mulet, Hui-Ping Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3597622?pdf=render

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http://europepmc.org/articles/PMC3597622?pdf=render

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