Aspartate β-hydroxylase as a target for cancer therapy

Abstract As metastasis is a major cause of death in cancer patients, new anti-metastatic strategies are needed to improve cancer therapy outcomes. Numerous pathways have been shown to contribute to migration and invasion of malignant tumors. Aspartate β-hydroxylase (ASPH) is a key player in the mali...

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Bibliographic Details
Main Authors: Madiha Kanwal, Michal Smahel, Mark Olsen, Jana Smahelova, Ruth Tachezy
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-020-01669-w