Evaluation of microRNA-223 and microRNA-125a expression association with STAT3 and Bcl2 genes in blood leukocytes of CLL patients: a case–control study

Evaluation of microRNA-223 and microRNA-125a expression association with STAT3 and Bcl2 genes in blood leukocytes of CLL patients: a case–control study

Abstract Objective In chronic lymphocytic leukemia (CLL), lack of expression or dysregulation of some special miRs disrupts apoptosis of malignant cells; thereby miR expression can enhance cell proliferation, disease progression and decrease patient survival. Results 30 CLL patients and 20 healthy i...

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Bibliographic Details
Main Authors: Nader Davari, Fatemeh Ahmadpour, Ali Asghar Kiani, Mozhgan Azadpour, Zari Tahannejad Asadi
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Research Notes
Subjects:
Chronic lymphocytic leukemia
MicroRNA-223
MicroRNA-125a
BCL2
STAT3
Prognostic
Online Access:https://doi.org/10.1186/s13104-020-05428-0

Internet

https://doi.org/10.1186/s13104-020-05428-0

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