Protective Role of Decorin in Primary Hepatocellular Carcinoma

Protective Role of Decorin in Primary Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) represents one of the most frequent type of primary liver cancers. Decorin, a small leucine-rich proteoglycan of the extracellular matrix, represents a powerful tumor cell growth and migration inhibitor by hindering receptor tyrosine kinases and inducing p21WAF1/CIP1....

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Bibliographic Details
Main Authors: Andrea Reszegi, Zsolt Horváth, Hajnalka Fehér, Barnabás Wichmann, Péter Tátrai, Ilona Kovalszky, Kornélia Baghy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
decorin (DCN)
hepatocellular carcinoma
proteoglycan (PG)
hepatocarcinogenesis
extracellular matrix (ECM)
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00645/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00645/full

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