Outcome Definition Influences the Relationship Between Genetic Polymorphisms of <em>ERCC1</em>, <em>ERCC2</em>, <em>SLC22A2</em> and Cisplatin Nephrotoxicity in Adult Testicular Cancer Patients

Outcome Definition Influences the Relationship Between Genetic Polymorphisms of <em>ERCC1</em>, <em>ERCC2</em>, <em>SLC22A2</em> and Cisplatin Nephrotoxicity in Adult Testicular Cancer Patients

Although previous research identified candidate genetic polymorphisms associated with cisplatin nephrotoxicity, varying outcome definitions potentially contributed to the variability in the effect size and direction of this relationship. We selected genetic variants that have been significantly asso...

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Bibliographic Details
Main Authors: Zulfan Zazuli, Leila S. Otten, Britt I. Drögemöller, Mara Medeiros, Jose G. Monzon, Galen E.B. Wright, Christian K. Kollmannsberger, Philippe L. Bedard, Zhuo Chen, Karen A. Gelmon, Nicole McGoldrick, Abhijat Kitchlu, Susanne J.H. Vijverberg, Rosalinde Masereeuw, Colin J.D. Ross, Geoffrey Liu, Bruce C. Carleton, Anke H. Maitland-van der Zee
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Genes
Subjects:
pharmacogenetics
cisplatin
nephrotoxicity
kidney injury
genetic polymorphisms
Online Access:https://www.mdpi.com/2073-4425/10/5/364

Internet

https://www.mdpi.com/2073-4425/10/5/364

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