Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

The mechanism through which Drosha and Dicer affect DNA repair is not clear. Here the authors use a high-throughput approach to uncover the role of Drosha in promoting DNA:RNA hybrids at DNA damaged sites.

Bibliographic Details
Main Authors: Wei-Ting Lu, Ben R. Hawley, George L. Skalka, Robert A. Baldock, Ewan M. Smith, Aldo S. Bader, Michal Malewicz, Felicity Z. Watts, Ania Wilczynska, Martin Bushell
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02893-x

Internet

https://doi.org/10.1038/s41467-018-02893-x

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