Increased methylglyoxal formation with upregulation of renin angiotensin system in fructose fed Sprague Dawley rats.

The current epidemic of obesity and type 2 diabetes is attributed to a high carbohydrate diet, containing mainly high fructose corn syrup and sucrose. More than two thirds of diabetic patients have hypertension. Methylglyoxal is a highly reactive dicarbonyl generated during glucose and fructose meta...

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Bibliographic Details
Main Authors: Indu Dhar, Arti Dhar, Lingyun Wu, Kaushik M Desai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769342?pdf=render