A hamster-derived West Nile virus isolate induces persistent renal infection in mice.

West Nile virus (WNV) can persist long term in the brain and kidney tissues of humans, non-human primates, and hamsters. In this study, mice were infected with WNV strain H8912, previously cultured from the urine of a persistently infected hamster, to determine its pathogenesis in a murine host.We f...

Full description

Bibliographic Details
Main Authors: Vandana Saxena, Guorui Xie, Bei Li, Tierra Farris, Thomas Welte, Bin Gong, Paul Boor, Ping Wu, Shao-Jun Tang, Robert Tesh, Tian Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3681636?pdf=render