GPCR-CARMA3-NF-kappaB Signaling Axis: A Novel Drug Target for Cancer Therapy
G protein-coupled receptors (GPCRs) play pivotal roles in regulating various cellular functions. It has been well established that GPCR activates NF-κB and aberrant regulation of GPCR-NF-κB signaling axis leads to cancers. However, how GPCRs induce NF-κB activation remains largely elusive. Recently,...
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| Format: | Article |
| Language: | English |
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China Anti-Cancer Association
2010-06-01
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| Series: | Cancer Biology & Medicine |
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| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/228 |