GPCR-CARMA3-NF-kappaB Signaling Axis: A Novel Drug Target for Cancer Therapy
G protein-coupled receptors (GPCRs) play pivotal roles in regulating various cellular functions. It has been well established that GPCR activates NF-κB and aberrant regulation of GPCR-NF-κB signaling axis leads to cancers. However, how GPCRs induce NF-κB activation remains largely elusive. Recently,...
Main Author: | Ji-yuan SUN |
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Format: | Article |
Language: | English |
Published: |
China Anti-Cancer Association
2010-06-01
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Series: | Cancer Biology & Medicine |
Subjects: | |
Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/228 |
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