CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells

<p>Abstract</p> <p>Background</p> <p>Interactions between CXCR4 and its ligand CXCL12 have been shown to be involved in cancer progression in colorectal cancer (CRC). We performed a comparative CXCL12/CXCR4 expression analysis and assessed the effect of external CXCL12...

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Bibliographic Details
Main Authors: Gräber Stefan, Vicinus Benjamin, Faust Sabrina K, Justinger Christoph, Wagner Mathias, Ghadjar Pirus, Frick Vilma O, Rubie Claudia, Kollmar Otto, Schilling Martin K
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/22