Reduction in the inflammatory markers CD4, IL-1, IL-6 and TNFα in dogs with keratoconjunctivitis sicca treated topically with mesenchymal stem cells

Reduction in the inflammatory markers CD4, IL-1, IL-6 and TNFα in dogs with keratoconjunctivitis sicca treated topically with mesenchymal stem cells

Keratoconjunctivitis sicca (KCS) is of predominantly immune-mediated origin. Dogs are an excellent model for understanding this disease, as the origin of KCS in dogs is like that in humans. The objective of this study was to localize and quantify immunological markers, such as CD4 lymphocytes, inter...

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Bibliographic Details
Main Authors: Marcos Rogério Sgrignoli, Danielle Alves Silva, Felipe Franco Nascimento, Danielle Antonelli Motta Sgrignoli, Gisele Alborghetti Nai, Márcia Guimarães da Silva, Michele Andrade de Barros, Maura Krähembühl Wanderley Bittencourt, Bruna Pereira de Morais, Heloíse Rangel Dinallo, Bruna Toledo Duran Foglia, Wellington Bott Cabrera, Elaine Carrion Fares, Silvia Franco Andrade
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119301552

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http://www.sciencedirect.com/science/article/pii/S1873506119301552

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