Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1

Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1

Abstract Interferons (IFNs) induce the expression of interferon-stimulated genes (ISGs) for defense against numerous viral infections, including classical swine fever virus (CSFV). However, the mechanisms underlying the effect of ISGs on CSFV infection are rarely reported. In this study, we demonstr...

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Bibliographic Details
Main Authors: Cheng Li, Yifan Wang, Hongqing Zheng, Wang Dong, Huifang Lv, Jihui Lin, Kangkang Guo, Yanming Zhang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-020-00753-5

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http://link.springer.com/article/10.1186/s13567-020-00753-5

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