Circular RNA circIKBKB promotes breast cancer bone metastasis through sustaining NF-κB/bone remodeling factors signaling

Circular RNA circIKBKB promotes breast cancer bone metastasis through sustaining NF-κB/bone remodeling factors signaling

Abstract Background Breast cancer (BC) has a marked tendency to spread to the bone, resulting in significant skeletal complications and mortality. Recently, circular RNAs (circRNAs) have been reported to contribute to cancer initiation and progression. However, the function and mechanism of circRNAs...

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Bibliographic Details
Main Authors: Yingru Xu, Shuxia Zhang, Xinyi Liao, Man Li, Suwen Chen, Xincheng Li, Xingui Wu, Meisongzhu Yang, Miaoling Tang, Yameng Hu, Ziwen Li, Ruyuan Yu, Mudan Huang, Libing Song, Jun Li
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Cancer
Subjects:
Bone metastasis
Breast cancer
circIKBKB
Bone remodeling factor
NF-κB
Online Access:https://doi.org/10.1186/s12943-021-01394-8

Internet

https://doi.org/10.1186/s12943-021-01394-8

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