Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy

Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disorder of the brain caused by reactivation of the JC virus (JCV), a polyomavirus that infects at least 60% of the population but is asymptomatic or results in benign symptoms in most people. PML occurs as a secondary disease...

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Bibliographic Details
Main Authors: Peggy S. Eis, Christopher D. Bruno, Todd A. Richmond, Igor J. Koralnik, Barbara A. Hanson, Eugene O. Major, Christina R. Chow, Houria Hendel-Chavez, Bruno Stankoff, Jacques Gasnault, Yassine Taoufik, Eli Hatchwell
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neurology
Subjects:
genetic risk
immunodeficiency
JC virus
multiple sclerosis
natalizumab
progressive multifocal leukoencephalopathy
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00186/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00186/full

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