High initial IgG antibody levels against Orientia tsutsugamushi are associated with an increased risk of severe scrub typhus infection.

High initial IgG antibody levels against Orientia tsutsugamushi are associated with an increased risk of severe scrub typhus infection.

<h4>Background</h4>Scrub typhus is a dominant cause of febrile illness in many parts of Asia. Immunity is limited by the great strain diversity of Orientia tsutsugamushi. It is unclear whether previous infection protects from severe infection or enhances the risk.<h4>Methods/princi...

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Bibliographic Details
Main Authors: Carol S Devamani, John A J Prakash, Neal Alexander, William Stone, Karthik Gunasekaran, Winsley Rose, Wolf-Peter Schmidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009283

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https://doi.org/10.1371/journal.pntd.0009283

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