The Mitochondrial Trigger in an Animal Model of Nonalcoholic Fatty Liver Disease

The Mitochondrial Trigger in an Animal Model of Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) is the leading liver chronic disease featuring hepatic steatosis. Mitochondrial β-oxidation participates in the derangement of lipid metabolism at the basis of NAFLD, and mitochondrial oxidative stress contributes to the onset of the disease. We evaluated the...

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Bibliographic Details
Main Authors: Guglielmina Chimienti, Antonella Orlando, Francesco Russo, Benedetta D’Attoma, Manuela Aragno, Eleonora Aimaretti, Angela Maria Serena Lezza, Vito Pesce
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Genes
Subjects:
NAFLD
mitochondrial biogenesis
mtDNA damage
DHEA
high fat-fructose diet
Online Access:https://www.mdpi.com/2073-4425/12/9/1439

Internet

https://www.mdpi.com/2073-4425/12/9/1439

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