Lung cancer chemotherapy using nanoparticles: Enhanced target ability of redox-responsive and pH-sensitive cisplatin prodrug and paclitaxel

Platinum-based combination therapy is more effective and less toxic, but lack of targeting, and is not capable to enrich in the tumor zone. To obstacle these drawbacks, prodrug and nanotechnology strategies have been investigated in this study. GSH-responsive and pH-responsive cisplatin prodrug was...

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Bibliographic Details
Main Authors: Baohua Wang, Wenxia Hu, Hongjiang Yan, Ge Chen, Yaozhong Zhang, Junjie Mao, Lei Wang
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221000342