A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells.

Human corneal fibroblasts (HCF) and corneal stromal stem cells (CSSC) each secrete and organize a thick stroma-like extracellular matrix in response to different substrata, but neither cell type organizes matrix on tissue-culture polystyrene. This study compared cell differentiation and extracellula...

Full description

Bibliographic Details
Main Authors: Dimitrios Karamichos, Martha L Funderburgh, Audrey E K Hutcheon, James D Zieske, Yiqin Du, Jian Wu, James L Funderburgh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897697?pdf=render