Enhancement of Immune Checkpoint Inhibitor-Mediated Anti-Cancer Immunity by Intranasal Treatment of <i>Ecklonia cava</i> Fucoidan against Metastatic Lung Cancer

Enhancement of Immune Checkpoint Inhibitor-Mediated Anti-Cancer Immunity by Intranasal Treatment of <i>Ecklonia cava</i> Fucoidan against Metastatic Lung Cancer

Although fucoidan, a well-studied seaweed-extracted polysaccharide, has shown immune stimulatory effects that elicit anticancer immunity, mucosal adjuvant effects via intranasal administration have not been studied. In this study, the effect of <i>Ecklonia cava</i>-extracted fucoidan (EC...

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Bibliographic Details
Main Authors: Wei Zhang, Juyoung Hwang, Dhananjay Yadav, Eun-Koung An, Minseok Kwak, Peter Chang-Whan Lee, Jun-O Jin
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Ecklonia cava</i> fucoidan
mucosal adjuvant
anti-PD-L1 antibody
immunotherapy
anti-cancer
Online Access:https://www.mdpi.com/1422-0067/22/17/9125

Internet

https://www.mdpi.com/1422-0067/22/17/9125

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