EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer.

Osteoblasts lining the inner surface of bone support hematopoietic stem cell differentiation by virtue of proximity to the bone marrow. The osteoblasts also modify their own differentiation by producing various isoforms of fibronectin (FN). Despite evidence for immune regulation by osteoblasts, ther...

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Bibliographic Details
Main Authors: Stephanie Rossnagl, Eva Altrock, Carla Sens, Sabrina Kraft, Katrin Rau, Michael D Milsom, Thomas Giese, Yvonne Samstag, Inaam A Nakchbandi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5031442?pdf=render