Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study

Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study

Cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) exhibit potent cardiovascular protective effects in preclinical models, and promoting the effects of EETs has emerged as a potential therapeutic strategy for coronary artery disease (CAD). The relationship between circulating EET levels...

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Bibliographic Details
Main Authors: Akinyemi Oni-Orisan, Matthew L. Edin, John Andrew Lee, Michael A. Wells, Erin S. Christensen, Kimberly C. Vendrov, Fred B. Lih, Kenneth B. Tomer, Xue Bai, Joan M. Taylor, George A. Stouffer, Darryl C. Zeldin, Craig R. Lee
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Lipid Research
Subjects:
arachidonic acid
atherosclerosis
eicosanoids
heart
inflammation
pharmacometabolomics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314061

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http://www.sciencedirect.com/science/article/pii/S0022227520314061

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