Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes.

Mean duration of recent infection (MDRI) and misclassification of long-term HIV-1 infections, as proportion false recent (PFR), are critical parameters for laboratory-based assays for estimating HIV-1 incidence. Recent review of the data by us and others indicated that MDRI of LAg-Avidity EIA estima...

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Main Authors: Yen T Duong, Reshma Kassanjee, Alex Welte, Meade Morgan, Anindya De, Trudy Dobbs, Erin Rottinghaus, John Nkengasong, Marcel E Curlin, Chonticha Kittinunvorakoon, Boonyos Raengsakulrach, Michael Martin, Kachit Choopanya, Suphak Vanichseni, Yan Jiang, Maofeng Qiu, Haiying Yu, Yan Hao, Neha Shah, Linh-Vi Le, Andrea A Kim, Tuan Anh Nguyen, William Ampofo, Bharat S Parekh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4339840?pdf=render