Identification and characterization of LRP8 (apoER2) in human blood platelets

Identification and characterization of LRP8 (apoER2) in human blood platelets

Recently, we reported that apoE inhibits platelet reactivity by stimulating NO release and postulated apoE-receptor activation of intracellular NO synthase (eNOS). Here, we implicate a low density lipoprotein receptor (LDL-R) family member by studying ligand requirements using purified apoE isoforms...

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Bibliographic Details
Main Authors: David R. Riddell, Dimitri V. Vinogradov, Anita K. Stannard, Nicholas Chadwick, James S. Owen
Format: Article
Language:English
Published: Elsevier 1999-10-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein E
apolipoprotein E receptor 2
intracellular signalling
LDL-receptor family
nitric oxide
platelet aggregation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349105

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http://www.sciencedirect.com/science/article/pii/S0022227520349105

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