High frequency of intron retention and clustered H3K4me3-marked nucleosomes in short first introns of human long non-coding RNAs

Abstract Background It is established that protein-coding exons are preferentially localized in nucleosomes. To examine whether the same is true for non-coding exons, we analysed nucleosome occupancy in and adjacent to internal exons in genes encoding long non-coding RNAs (lncRNAs) in human CD4+ T c...

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Bibliographic Details
Main Authors: Pinki Dey, John S. Mattick
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-021-00419-2