1,4-Disubstituted 1<i>H</i>-1,2,3-Triazoles for Renal Diseases: Studies of Viability, Anti-Inflammatory, and Antioxidant Activities

1,4-Disubstituted 1<i>H</i>-1,2,3-Triazoles for Renal Diseases: Studies of Viability, Anti-Inflammatory, and Antioxidant Activities

Inflammation is a hallmark of many metabolic diseases. We previously showed that ferrocene-appended 1<i>H</i>-1,2,3-triazole hybrids inhibit nitric oxide (NO) production in in vitro models of lipopolysaccharide-induced inflammation in the BV-2 cell. In the present study, we explored the...

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Bibliographic Details
Main Authors: Ching-Yi Cheng, Ashanul Haque, Ming-Fa Hsieh, Syed Imran Hassan, Md. Serajul Haque Faizi, Necmi Dege, Muhammad S. Khan
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
tumor necrosis factor-α (TNF-α)
cytosolic phospholipase A<sub>2</sub> (cPLA<sub>2</sub>)
prostaglandin E<sub>2</sub> (PGE<sub>2</sub>)
matrix metalloproteinase-9 (MMP-9)
inducible nitric oxide synthase (iNOS)
Online Access:https://www.mdpi.com/1422-0067/21/11/3823

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https://www.mdpi.com/1422-0067/21/11/3823

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